The Remarkable Journey of Susi Ramstein: The First LSD Trip-Sitter
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The Historic Role of Susi Ramstein
In the annals of psychedelic history, Susi Ramstein holds a unique position as the first individual to facilitate an LSD experience. She was not only a key figure in the life of Albert Hofmann—the scientist who first synthesized LSD—but also the first woman to engage in this groundbreaking journey.
LSD-25, the 25th alkaloid derived from the Ergot fungus, was synthesized by Hofmann, who followed a laboratory protocol that involved testing new substances among the lab team. On April 19, 1943, Hofmann deliberately ingested a 250-microgram dose of LSD-25, marking the inception of the first-ever LSD trip. Realizing that he had underestimated the potency of this psychedelic, he invited his assistant, the 21-year-old Susi Ramstein, to accompany him home.
Due to wartime fuel restrictions in Europe, both Hofmann and Susi cycled to their workplace. When the psychedelic effects became overwhelming, Hofmann opted to return home. With his wife absent, Susi played a crucial role in guiding Hofmann through a significant and pleasurable psychedelic experience.
At the onset, both Susi and Hofmann were alarmed by the intensity of the effects, fearing he might be in danger. Susi contacted a physician, who reassured them that there was no serious cause for concern apart from Hofmann's dilated pupils. This confirmation allowed Hofmann to relax and embrace the experience.
The Initial Encounter with LSD
On Monday, April 19, 1943, Hofmann's planned encounter with LSD followed an accidental exposure just days earlier. On April 16, he had inadvertently absorbed LSD through his skin, leading to dizzy spells and a cascade of vivid visions that captivated him.
“At home, I lay down, immersed in a blissful, intoxicated state characterized by an extraordinarily active imagination…” — Albert Hofmann, LSD, My Problem Child
During his deliberate trip, Hofmann began to notice peculiar sensations and distortions. He experienced dizziness, anxiety, and visual alterations as he pedaled home. Upon arrival, the trip intensified alarmingly; he perceived his surroundings as warped and threatening, while moments of clarity emerged amidst the chaos.
As the intensity heightened, Hofmann felt as if he were losing his grip on reality. His perception shifted, allowing him to witness his own experience from an outsider’s perspective, which induced a profound fear of insanity.
“Hours later, as my fear ebbed, I found myself enveloped in swirling colors and shapes…” — Hofmann, LSD, My Problem Child
Gradually, he regained a sense of normalcy and began to appreciate the intricate patterns and colors that danced behind his closed eyes.
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The Experience of Synesthesia
One notable aspect of Hofmann's trip was the phenomenon of synesthesia. He described how sounds morphed into vivid visual images, creating a unique and immersive sensory experience.
“Every sound transformed into a vivid visual, each with its own form and color…” — Hofmann, LSD, My Problem Child
As the experience waned, Susi informed Hofmann's wife of the events, and the three engaged in a conversation, albeit with Hofmann still recovering from the profound effects of LSD. Eventually, he fell asleep, awakening the next morning revitalized, with a newfound zest for life.
Hofmann's day began with a delightful breakfast, enhanced by a heightened sense of taste and appreciation for his surroundings, which felt freshly awakened after a spring rain.
The Pioneering Journey of Susi Ramstein
Born in 1922, Susi was the only woman working at the Sandoz research lab where Hofmann conducted his experiments. She initially obtained her chemical handling license at the young age of 20, ultimately becoming Hofmann’s assistant and participating in the groundbreaking LSD research.
At the time, self-experimentation with newly synthesized compounds was commonplace among chemists. Following Hofmann’s lead, many lab members also ventured into the psychedelic realm, including Susi, who bravely ingested doses exceeding 100 micrograms.
Susi reported that her experience was mild, bringing about beautiful visions and a sense of joy without disorientation. Choosing not to ride her bicycle home, she opted for the tram instead.
During her tram ride, she found herself amused by the exaggerated features of the conductor and fellow passengers, feeling a light-heartedness that accompanied her experience.
At just 21, Susi became the first woman to facilitate an LSD trip, marking a significant milestone in the history of psychedelics.
The Future of Psychedelics
In the years following these pioneering experiences, lab members, including Susi, continued to explore the effects of LSD-25. Subsequently, an LSD-based medication known as Delysid was developed for therapeutic use.
However, the onset of prohibition stifled psychedelic research for decades. As of 2023, there is a resurgence in interest surrounding responsible psychedelic use as a viable approach to addressing mental health issues like depression, anxiety, and PTSD—potentially offering a more effective alternative to conventional pharmaceuticals.
In this context, it is vital to establish frameworks for psychedelic integration and harm reduction, ensuring safe experiences while guiding individuals in understanding and utilizing their psychedelic journeys for positive life changes.
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